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How does LDN help with multiple sclerosis (MS) in functional medicine clinic?

Updated: Aug 9

Recently I saw a client whose multiple sclerosis (MS) symptoms have disappeared. When I asked her if she feels she has reached remission, she said yes - definitely. One of the ways I can tell when someone has reached remission from an autoimmune condition is when that person can begin to forget about the fact they have or they had an autoimmune condition, in this case MS.


In these situations, I feel so fortunate to be a privileged observer witnessing a miracle of healing through LDN. This is one reason why since when I learned about LDN (from a patient who asked me to research about LDN about 20 years ago), I continued to use LDN, write about LDN, and give lectures about LDN.


Functional medicine offers a personalized approach to managing multiple sclerosis (MS), focusing on addressing the root causes and symptoms of the disease rather than just treating the symptoms. Here's how functional medicine might help with MS:

1. Personalized Assessment

  • Comprehensive Testing: Functional medicine practitioners often conduct extensive testing to identify triggers and imbalances in the body, including nutrient deficiencies, hormonal imbalances, and gut health issues such as micronutrient testing.

  • Genetic Factors: They may also explore genetic predispositions that could influence disease progression or treatment response such as 3 x 4 genetic testing.

2. Nutritional Support

  • Anti-Inflammatory Diet: Diet plays a crucial role in managing MS. Functional medicine often emphasizes an anti-inflammatory diet rich in whole foods, healthy fats, and antioxidants to reduce inflammation and support overall health.

  • Nutrient Optimization: Addressing deficiencies in vitamins and minerals, such as vitamin D, B vitamins, and omega-3 fatty acids, can be essential, as these nutrients are known to support neurological function and reduce inflammation.

3. Gut Health

  • Microbiome Balance: There is growing evidence that gut health is linked to autoimmune conditions like MS. Functional medicine might focus on restoring a healthy gut microbiome through diet, probiotics, and other interventions. This can be achieved by using GI Map tests.

  • Leaky Gut Syndrome: Addressing intestinal permeability, also known as "leaky gut," can help reduce autoimmune reactions that may exacerbate MS symptoms.

4. Stress Management

  • Mind-Body Techniques: Functional medicine often incorporates stress-reduction techniques such as meditation, yoga, and other mind-body practices, recognizing that stress can exacerbate MS symptoms.

  • Adrenal Support: Supporting the adrenal glands and balancing cortisol levels can be crucial, as chronic stress is a known trigger for autoimmune flare-ups.

5. Detoxification

  • Environmental Toxins: Functional medicine practitioners may assess exposure to environmental toxins (like heavy metals) and implement detoxification strategies to reduce the toxic load on the body, which might help in reducing MS symptoms.

6. Lifestyle Modifications

  • Exercise and Movement: Regular, moderate exercise tailored to the individual's abilities can help maintain muscle strength and improve mobility, while also reducing fatigue.

  • Sleep Optimization: Improving sleep quality is another focus, as poor sleep can worsen MS symptoms.

7. Targeted Supplementation

  • Immune System Modulation: Specific supplements might be recommended to modulate the immune system, reducing the intensity of the autoimmune response that characterizes MS.

  • Neuroprotection: Supplements aimed at protecting nerve cells and reducing oxidative stress may also be part of the treatment plan.

8. Holistic Approach

  • Whole-Body Focus: Functional medicine views the body as an interconnected system, so treatment often involves addressing multiple aspects of health simultaneously, rather than focusing solely on MS symptoms.

By taking a holistic, individualized approach, functional medicine aims to improve the quality of life for people with MS, potentially slowing disease progression and alleviating symptoms. However, it is essential for individuals to work closely with both their conventional neurologist and a qualified functional medicine practitioner to ensure a safe and effective treatment plan.


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