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Writer's pictureJohn Kim

How can LDN help with a patient with Hashimoto's thyroiditis and tinnitus in a functional medicine clinic?

Recently saw a patient with Hashimoto's thyroiditis and tinnitus. At a glance, two conditions appear unrelated.


Hashimoto's thyroiditis is an autoimmune condition where the immune system attacks the thyroid gland, leading to hypothyroidism (underactive thyroid). The cause of tinnitus remains unknown. In my training with Dr. Andrew Weil, I learned that complex phenomena can be organized through commonalities.


In my clinic, LDN is used to normalize immune function and to normalize nervous system. Using this approach, Hashimoto's thyroiditis is an autoimmune condition and tinnitus can be caused by inflammation/irritation of auditory nerve.


After taking LDN, patient's thyroid medications had to be reduced (as her thyroid functional began to normalize) and her tinnitus improved > 90%.




Functional medicine aims to address the root cause of diseases by considering the whole person—body, mind, and lifestyle. Here's an overview of how Hashimoto's thyroiditis might be treated using functional medicine principles:

1. Comprehensive Assessment

  • Thyroid Panel: A detailed thyroid panel, including TSH, Free T3, Free T4, Reverse T3, and thyroid antibodies (TPO and TG antibodies), is crucial to assess thyroid function.

  • Nutritional Deficiencies: Check for deficiencies in vitamins and minerals like vitamin D, B12, selenium, iodine, and zinc, which are important for thyroid health.

  • Gut Health: Assess gut health through tests for leaky gut, dysbiosis (imbalance in gut bacteria), and potential infections, as gut health is closely linked to immune function.

  • Adrenal Function: Evaluate adrenal function, as chronic stress and adrenal fatigue can exacerbate thyroid issues.

  • Toxins and Heavy Metals: Exposure to toxins and heavy metals can contribute to autoimmune conditions, so testing for these may be recommended.

2. Dietary Interventions

  • Anti-Inflammatory Diet: An anti-inflammatory diet can help reduce autoimmune reactions. This may include eliminating gluten, dairy, soy, and processed foods, which can trigger inflammation in some people.

  • Autoimmune Protocol (AIP) Diet: The AIP diet is a more restrictive version of the paleo diet that focuses on healing the gut and reducing inflammation by eliminating potential food triggers.

  • Nutrient-Rich Foods: Include foods rich in selenium (Brazil nuts), zinc (pumpkin seeds), and iodine (seaweed), which are essential for thyroid health.

  • Gluten-Free Diet: Many people with Hashimoto's have gluten sensitivity or celiac disease, so a gluten-free diet is often recommended.

3. Gut Health Support

  • Probiotics and Prebiotics: Support gut health with probiotics and prebiotics to restore a healthy balance of gut bacteria.

  • Digestive Enzymes: Consider digestive enzymes if there is evidence of poor digestion or malabsorption.

  • Leaky Gut Treatment: Address leaky gut with supplements like L-glutamine, which can help heal the intestinal lining.

4. Stress Management

  • Mind-Body Practices: Techniques like meditation, yoga, and deep-breathing exercises can help manage stress, which is a key factor in autoimmune conditions.

  • Adrenal Support: Adaptogenic herbs like ashwagandha, rhodiola, and holy basil can support adrenal function and reduce stress.

5. Detoxification

  • Toxin Reduction: Reduce exposure to environmental toxins such as pesticides, BPA, and heavy metals.

  • Detox Support: Support the body's natural detoxification processes with liver-supportive foods (like cruciferous vegetables) and supplements (such as milk thistle).

6. Targeted Supplementation

  • Selenium: Selenium can help reduce thyroid antibodies and support thyroid function.

  • Vitamin D: Adequate vitamin D levels are crucial for immune system regulation.

  • Omega-3 Fatty Acids: These have anti-inflammatory properties and can support overall immune health.

  • Thyroid-Specific Nutrients: Consider supplements containing iodine, zinc, and B vitamins, but only under the guidance of a healthcare professional, as excessive iodine can be harmful.

7. Hormone Replacement Therapy

  • Bioidentical Hormones: In some cases, functional medicine practitioners might recommend natural desiccated thyroid hormone or bioidentical hormones instead of synthetic thyroid hormones like levothyroxine.

  • Regular Monitoring: Regular monitoring of thyroid levels and symptoms is essential to ensure proper hormone balance.

8. Lifestyle Modifications

  • Exercise: Regular, moderate exercise can help improve metabolism and support overall health.

  • Sleep: Prioritize sleep, as poor sleep can worsen autoimmune conditions.

  • Community and Support: Engaging in supportive communities and reducing social stressors can positively impact health.

9. Personalized Treatment

  • Genetic Considerations: Some functional medicine practitioners may evaluate genetic factors that could influence treatment, such as MTHFR mutations, which affect folate metabolism.

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